Mahito is an antagonist in the Jujutsu Kaisen series. He is a cursed spirit allied with Pseudo-Geto. His goal is the eradication of humanity and ultimately replacing the population with cursed spirits.
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All For One is the main antagonist of the My Hero Academia. He is the founder of the League of Villains. His ability to steal any Quirk from his opponent makes All For One impossible to defeat
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Sōsuke Aizen is the former captain of the 5th Division in the Gotei 13. After waging war against Soul Society with an army of Arrancar, He was defeated by Ichigo Kurosaki and was sealed away.
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Frieza is the main antagonist of the Dragon Ball series. He is the leader of his own imperialist army and desires to conquer Universe 7. He is feared throughout the universe for his ruthlessness and power.
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Muzan Kibutsuji is the main antagonist of Demon Slayer: He is the Demon King, the first of his kind, as well as the progenitor of all other demons in existence. He is also the leader of the Twelve Kizuki,
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Zeke Yeager was the former Captain of Marley's Warrior Unit, assigned to take the Founding Titan from the Eldians of Paradis Island. He was the inheritor of the Beast Titan.
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Dio Brando, After becoming a vampire and later a Stand user, is responsible for many major events of the series, from the death of Jonathan Joestar to his Family's sudden acquisition of Stand power
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Wrath is a major antagonist in Fullmetal Alchemist. He is the ruler of the country of Amestris, but he is later revealed to be one of the Seven Homunculi created by the mysterious being known as Father.
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Hisoka Morow, is one of the main antagonists of Hunter x Hunter. He is a former associate of the Phantom Troupe and a magician & serial killer who is always in search for strong opponents.
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Madara Uchiha is the main antagonist of the Naruto series. He is the co-founder of the village of Konohagakure and its first Rogue Ninja. He planned to rule the Ninja World as a god.
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Gilgamesh is the antagonist of Fate Series. He is the Archer-class servant of Tokiomi Tohsaka and later forms a contract with Kirei that lasts ten years later. He has an obsession with Saber.
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Bondrewd, known as the "Lord of Dawn", is the main antagonist of the Idolfront arc from Made in Abyss. He is a White Whistle, but is known to be exceptionally cruel even by the standards of his peers.
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Shogo Makishima is the main antagonist of the first season of Psycho-Pass. He is a mysterious criminal who is unable to be detected by the Sibyl System, and the archenemy of Shinya Kogami.
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Light Yagami is the main protagonist of the Death Note series. After discovering the Death Note, he decides to use it to rid the world of criminals. His killings are labelled as the work of "Kira."
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Griffith is the founder and leader of the mercenary army known as the Band of the Hawk. He used the eclipse to sacrifice his entire army and later was reborn as Femto. He is the arch-nemesis of Guts.
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